Identification of Salmonella enterica serovar Typhi strain from a young Brazilian patient: the relevance of automated microbiological methods for the rapid diagnosis of systemic infections

Max R. Batista-Araújo; Luisa  Ferreira-Seabra; Lincoln Oliveira-Sant’Anna; Louisy  Sanches dos Santos

doi:10.54034/mic.e1295

Authors

Max R. Batista-Araújo Hermes Pardini Institute, Vespasiano, Minas Gerais, Brazil https://orcid.org/0000-0002-3293-8496
Luisa Ferreira-Seabra Hermes Pardini Institute, Vespasiano, Minas Gerais, Brazil
Lincoln Oliveira-Sant’Anna Rio de Janeiro State University, Rio de Janeiro, Brazil https://orcid.org/0000-0002-6933-8961
Louisy Sanches dos Santos Rio de Janeiro State University, Rio de Janeiro, Brazil https://orcid.org/0000-0002-5303-6395

DOI:

https://doi.org/10.54034/mic.e1295

Keywords:

Salmonellosis, Salmonella Typhi, Typhoid fever, MALDI-TOF MS, Blood culture

Abstract

Introduction: Latin American countries have public health problems that are aggravated by inadequate basic sanitary conditions. Inefficient vaccination coverage, as well as the fact that a significant portion of the population is exposed to contaminated water and food, can lead to an increase in the incidence of some diseases. Methodology: the work reports a case of infection by Salmonella enterica serovar Typhi (S. Typhi), whose contagion is strictly related to personal and environmental hygiene conditions. Conclusion: accurate identification and immediate detection of the etiologic agent using automated methods, such as Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) and the BACT / ALERT System® 3D, can positively contribute to the patient's prognosis and therapeutic success. Thus, principally in the Latin American, a quick and adequate treatment is of great importance, both for the patient and to minimize the spread of multidrug-resistant strains and the consequent reduction of therapeutic options.

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