Complicaciones cardiovasculares de la COVID-19 en pacientes hospitalizados, revisión sistemática de la literatura

Autores/as

DOI:

https://doi.org/10.35839/repis.5.3.1054

Palabras clave:

SARS-CoV-2, COVID-19, sistema cardiovascular, anomalías cardiovasculares

Resumen

Antecedentes: La enfermedad del COVID-19 causado por el virus, SARS-CoV-2, comenzó en la región de Wuhan de la República Popular de China, a finales del 2019, generando complicaciones y mortalidad en pacientes hospitalizados. Objetivo: Revisar la literatura de manera sistemática sobre las complicaciones cardiovasculares de la COVID-19 en pacientes hospitalizados. Métodos: Se incluyeron estudios observacionales, estudios sobre complicaciones cardiovasculares en pacientes hospitalizados por COVID-19, estudios con textos disponibles y estudios en idioma inglés y español. Se realizó una síntesis narrativa de los datos recopilados, sin un análisis formal estadístico. Además, de análisis cualitativo de las principales patologías y manifestaciones clínicas notificadas. Se empleo la herramienta de la calidad del estudio de los Institutos Nacionales de Salud de los Estados Unidos. Resultados: En esta revisión se observó que el 50.6 % de los pacientes infectados por el SARS-CoV-2, padecieron alguna comorbilidad cardiovascular (43.5 % hipertensión arterial (HTA) y 19.8 % diabetes mellitus). Las complicaciones del COVID-19 en pacientes infectados fueron: (44.1 %) tromboembolismo venoso, (32 %) infarto agudo de miocardio (IMA), (19.2 %) miocarditis, (16.3 %) arritmia y (11.2 %) enfermedad cerebrovascular. Conclusión: Los principales efectos cardiovasculares en pacientes infectados por el SARS-COV-2 fueron miocarditis, infarto agudo de miocardio (IAM), tromboembolismo venoso, enfermedad cerebro vascular (ECV).

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Biografía del autor/a

Henry Mejia-Zambrano, Universidad Privada San Juan Bautista, Lima, Perú

Estudiante de Medicina Humana

Livia Ramos-Calsín, Centro de Salud Mental Comunitario San Borja – MINSA, Lima, Perú

Licenciada en Enfermería

Citas

Machhi J, Herskovitz J, Senan A, Dutta D, Nath B, Oleynikov M. The Natural History, Pathobiology, and Clinical Manifestation of SARS-CoV-2 Infections. J Neuroimmune Pharmacol [Internet]. 2020 [citado 8/03/2021]; 15(3): 1-28. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373339/

Organización Mundial de la Salud. Tablero COVID-19 [Internet]. Organización Mundial de la Salud; [citado el 07/05/2021]. Disponible: https://covid19.who.int/.

Dhakal B, Sweitzer N, Indik J, Acharya D, William P. SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart. Heart Lung Circ [Internet]. 2020 [citado 8/03/2021]; 29(7): 937-987. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274628/

Alwaqfi N, Ibrahin K. Covid-19: An update and cardiac involvement. J Cardiothorac Surg [Internet]. 2020 [citado 8/03/2021]; 15(1): 239. Disponible: https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01299-5

Madjid M, Safavi-Naeni P, Solomon S, Vardeny O. Potential Effects of Coronaviruses on the Cardiovascular System: A Review. JAMA Cardiology [Internet]. 2020 [citado 8/03/2021]; 5(7): 831-840. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2763846

Bansal M. Cardiovascular disease and Covid-19. Diabetes and Metabolic Syndrome: Clinical Research and Reviews [Internet]. 2020 [citado 8/03/2021]; 14(3): 247-250. Disponible: https://pubmed.ncbi.nlm.nih.gov/32247212/

Kohli U, Lodha R. Cardiac Involvement in Children with Covid-19. Indian Pediatrics [Internet]. 2020 [citado 8/03/2021]; 57(10): 936-940. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605469/

Jiang L, Tang K, Levin M, Irfan O, Morris S, Wilson K. Covid-19 and multisystem inflammatory Syndrome in Children and adolescents. Lancet Infect Dis [Internet]. 2020 [citado 8/03/2021]; 20(11): 276-288. Disponible: https://pubmed.ncbi.nlm.nih.gov/32818434/

Nishiga M, Wang D, Han Y, Lewis D, Wu J. Covid-19 and Cardiovascular disease: from basic mechanisms to clinical perspectives. Nat Rev Cardiol [Internet]. 2020 [citado 8/03/2021]; 17(9): 543-558. Disponible: https://pubmed.ncbi.nlm.nih.gov/32690910/

Wang D, Hu B, Hu C, F Zhu, X Liu, J Zhang. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA [Internet]. 2020 [citado 8/03/2021]; 323(11): 1061-1069. Disponible: https://jamanetwork.com/journals/jama/fullarticle/2761044

Li B, Yang J, Zhao F, Zhi L, Wang X, Liu L. Prevalence and impacto of cardiovascular metabolic diseases on COVID-19 in China. Clin Res Cardiol [Internet]. 2020 [citado 8/03/2021]; 109(5): 531-538. Disponible: https://pubmed.ncbi.nlm.nih.gov/32161990/

Richardson S, Hirsch J, Narasimhan M. Presenting Characteristics, Comorbidities, and Outcomes among 5700 Patients Hospitalized with COVID-19 in the New York City Area. JAMA [Internet]. 2020 [citado 8/03/2021]; 323(20): 2052-2059. Disponible: https://jamanetwork.com/journals/jama/fullarticle/2765184

Puntmman V, Carerj M, Wieters I, Fahim M, Arendt C, Hoffmann J. Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered from Coronavirus Disease 2019 (COVID-19). JAMA Cardiol [Internet]. 2020 [citado 8/03/2021]; 5(11): 1265-1273. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2768916

Guo T, Fan Y, Chen M, Wu X, Zhang L, He T. Cardiovascular Implications of Fatal Outcomes of Patients with Coronavirus Disease 2019 (COVID-19). JAMA Cardiol [Internet]. 2020 [citado 8/03/2021]; 5(7): 811-818. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2763845

Starekova J, Bluemke D, Bradham W, Eckhardt L, Grist T, Kusmirek J. Evaluation for Myocarditis in Competitive Student Athletes Recovering from Coronavirus Disease 2019 with Cardiac Magnetic Resonance Imaging. JAMA Cardiol. [Internet]. 2020 [Citado 08/03/2021];14: e207444. Disponible en: https://jamanetwork.com/journals/jamacardiology/fullarticle/2775372

Rosenthal N, Cao Z, Gundrum J, Sianis J, Safo S. Risk Factors Associated With In-Hospital Mortality in a US National Sample of Patients With COVID-19. JAMA Netw Open. [Internet]. 2020 [Citado 09/03/2021]; 3(12): e2029058. Disponible en: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2773971

Iciardi R, Lupi L, Zaccone G, Italia L, Raffo M, Tomasoni D. Cardiac Involvement in a Patient with Coronavirus Disease 2019 (COVID-19). JAMA Cardiol [Internet]. 2020 [citado 9/03/2021]; 5(7): 819-824. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2763843

Lindner D, Fitzek A, et al. Association of Cardiac Infection with SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiol. [Internet]. 2020 [Citado 09/03/2021]; 5(11):1281-1285. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2768914

Mortus J, Manek S, Brubaker L, Loor M, Cruz M, Trautner B. Thromboelastographic Results and Hypercoagulability Syndrome in Patients with Coronavirus Disease 2019 Who Are Critically Ill. JAMA Netw Open [Internet]. 2020 [citado 9/03/2021]; 3(6): e2011192. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275245/

Wu Z, McGoogan J. Characteristics of and Important Lessons from the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases from the Chinese Center for Disease Control and Prevention. JAMA - Journal of the American Medical Association [Internet]. 2020 [citado 9/03/2021]; 323(13): 1239-1242. Disponible: https://jamanetwork.com/journals/jama/fullarticle/2762130

Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F. Association of Cardiac Injury with Mortality in Hospitalized Patients with COVID-19 in Wuhan, China. JAMA Cardiol [Internet]. 2020 [citado 9/03/2021]; 5(7): 802-810. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2763524

Zhang S, Liu Y, Wang X, Yang L, Li H, Wang Y. SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19. J Hematol Oncol [Internet]. 2020 [citado 9/03/2021]; 13(1):120. Disponible: https://jhoonline.biomedcentral.com/articles/10.1186/s13045-020-00954-7

Gerstein N, Venkataramani R, Goumas A, Chapman N, Deriy L. COVID-19-Related Cardiovascular Disease and Practical Considerations for Perioperative Clinicians. Semin Cardiothorac Vasc Anesth [Internet]. 2020 [citado 9/03/2021]; 24(4): 293-303. Disponible: https://pubmed.ncbi.nlm.nih.gov/32706293/

Zheng Y, Ma Y, Zhang J, Xie X. COVID-19 and the cardiovascular system. Nature Reviews Cardiology [Internet]. 2020 [citado 9/03/2021]; 17(5): 259-260. Disponible: https://pubmed.ncbi.nlm.nih.gov/32139904/

Vaduganathan M, Vardeny O, Michel T, Mc Murray J, Pfeffer M, Solomon M. Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19. New England Journal of Medicine [Internet]. 2020 [citado 9/03/2021]; 382(17): 1653-1659. Disponible: http://www.nejm.org/doi/10.1056/NEJMsr2005760

Fosbol E, Butt J, Ostergaard L, Andersson C, Selmer C, Kragholm K, Schou M, et al. Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use with COVID-19 Diagnosis and Mortality [Internet]. 2020 [citado 9/03/2021]; 324(2): 168-177. Disponible: https://jamanetwork.com/journals/jama/fullarticle/2767669

Kolte D, Libby P, Jang I. New Insights into Plaque Erosion as a Mechanism of Acute Coronary Syndromes. JAMA - Journal of the American Medical Association [Internet]. 2021 [citado 9/03/2021]; 325 (11): 1043. Disponible: https://jamanetwork.com/journals/jama/fullarticle/2776938

Gluckman T, Wilson M, Chiu S, Penny B, Chepuri V, Waggoner J, et al. Case Rates, Treatment Approaches, and Outcomes in Acute Myocardial Infarction during the Coronavirus Disease 2019 Pandemic. JAMA Cardiology [Internet]. 2020 [citado 10/03/2021]; 5(12): 1419-1424. Disponible: https://jamanetwork.com/journals/jamacardiology/fullarticle/2769293

Song C, Liu S, Yin D, Wang Y, Zhao Y, Yang W, et al. Impact of Public Health Emergency Response to COVID-19 on Management and Outcome for STEMI Patients in Beijing—A Single-Center Historic Control Study. Current Problems in Cardiology [Internet]. 2021 [citado 10/03/2021]; 46(3): 100693. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7462598/

Rosenberg E, Dufort E, Udo T, Wilberschied L, Kumar J, Tesoriero J, et al. Association of Treatment with Hydroxychloroquine or Azithromycin with In-Hospital Mortality in Patients with COVID-19 in New York State. JAMA - Journal of the American Medical Association [Internet]. 2020 [citado 10/03/2021]; 323 (24): 2493-2502. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215635/

Dobesh P, Trujillo T. Coagulopathy, Venous Thromboembolism, and Anticoagulation in Patients with COVID-19. Pharmacotherapy [Internet]. 2020 [citado 10/03/2021]; 40(11): 1130-1151. Disponible: https://onlinelibrary.wiley.com/doi/10.1002/phar.2465

Fan H, Tang X, Song Y, Liu P, Chen Y. Influence of covid-19 on cerebrovascular disease and its possible mechanism. Neuropsychiatric Disease and Treatment [Internet]. 2020 [citado 10/03/2021]; 16: 1359-1367. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266513/

Merkler A, Parikh N, Mir S, Gupta A, Kamel H, Lin E, et al. Risk of Ischemic Stroke in Patients with Coronavirus Disease 2019 (COVID-19) vs Patients with Influenza. JAMA Neurology [Internet]. 2020 [citado 10/03/2021]; 7(1): 1366-1372. Disponible: https://jamanetwork.com/journals/jamaneurology/fullarticle/2768098

Ramírez P, Gordon M, Martin-Cerezuela M, Villareal E, Sancho E, Padros M, et al. Acute respiratory distress syndrome due to COVID-19. Clinical and prognostic features from a medical Critical Care Unit in Valencia, Spain. Medicina Intensiva [Internet]. 2021 [citado 10/03/2021]; 45(1): 27-34. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836701/

Luo J, Zhu X, Jian J, Chen X, Yin K. Cardiovascular disease in patients with COVID-19: evidence from cardiovascular pathology to treatment. Acta Biochimica et Biophysica Sinica [Internet]. 2021 [citado 10/03/2021]; 176. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7929476/

Chan X, Win Y, Haeusler I, Tan J, Loganathan S, Saralamba S, et al. Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data. PLoS medicine [Internet]. 2020 [citado 11/03/2021]; 17(3): e1003040. Disponible: https://dx.plos.org/10.1371/journal.pmed.1003040

Publicado

2021-07-01 — Actualizado el 2021-08-05

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Mejia-Zambrano H, Ramos-Calsín L. Complicaciones cardiovasculares de la COVID-19 en pacientes hospitalizados, revisión sistemática de la literatura. Rev Peru Investig Salud [Internet]. 5 de agosto de 2021 [citado 28 de septiembre de 2021];5(3):213-20. Disponible en: http://revistas.unheval.edu.pe/index.php/repis/article/view/1054

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