Microbiological isolates of Comamonas testoteroni from strains found in patients with acute appendicitis. A Case series

Galo G. Farfán-Cano

doi:10.54034/mic.e1833

Authors

Galo G. Farfán-Cano Society of Infectious Diseases of Guayas, Guayaquil - Ecuador https://orcid.org/0000-0001-8447-5764

DOI:

https://doi.org/10.54034/mic.e1833

Keywords:

intraabdominal infections, appendicitis, comamonas, comamonas testosteroni

Abstract

Acute appendicitis is the leading cause of urgent surgery. Recently, there have been several case reports linking Comamonas, a globally distributed environmental bacterial species, to appendicitis. The patients described below were admitted through the emergency room of a second-level hospital unit in Guayaquil city, presenting symptoms consistent with acute abdomen and initially diagnosed with acute appendicitis prior to surgical intervention. In all cases, surgical or pediatric surgical services collected microbiological samples for further analysis, and the results are detailed below.

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References

Parrilla P, Luján J, Hernández Q. Apendicitis Aguda. In Manual de la Asociación Española de Cirujanos.. 2a ed. Madrid: Médica Panamericana; 2011.

Sellars H, Boorman P. Acute appendicitis. Surgery (Oxford). 2017;35(8): 432–438. https://doi.org/10.1016/j.mpsur.2017.06.002.

Ávila M, García M. Apendicitis aguda: revisión de la presentación histopatológica en Boyacá, Colombia. Revista Colombiana de Cirugía. 2015;2015(30): 125–130.

Bhangu A, Søreide K, Di Saverio S, Assarsson JH, Drake FT. Acute appendicitis: modern understanding of pathogenesis, diagnosis, and management. The Lancet. 2015;386(10000): 1278–1287. https://doi.org/10.1016/S0140-6736(15)00275-5.

Farooq S, Farooq R, Nahvi N. Comamonas testosteroni: Is It Still a Rare Human Pathogen. Case Reports in Gastroenterology. 2017;11(1): 42–47. https://doi.org/10.1159/000452197.

Almuzara MN, Cittadini R, Vera Ocampo C, Bakai R, Traglia G, Ramirez MS, et al. Intra-Abdominal Infections Due to Comamonas kerstersii. Journal of Clinical Microbiology. 2013;51(6): 1998–2000. https://doi.org/10.1128/JCM.00659-13.

Tartar AS, Tartar T. A Rare Pathogen in Acute Appendicitis: Two Cases with Comamonas testosteroni Infection and Literature Review. Journal of Pediatric Infectious Diseases. 2020;15(02): 110–112. https://doi.org/10.1055/s-0038-1641604.

Farshad S, Norouzi F, Aminshahidi M, Heidari B, Alborzi A. Two cases of bacteremia due to an unusual pathogen, Comamonas testosteroni in Iran and a review literature. The Journal of Infection in Developing Countries. 2012;6(06): 521–525. https://doi.org/10.3855/jidc.2215.

Berman JJ. Bacteria. In: Taxonomic Guide to Infectious Diseases. Elsevier; 2019. p. 39–119. https://doi.org/10.1016/B978-0-12-817576-7.00003-1 [Accessed 1st March 2023].

Ryan MP, Sevjahova L, Gorman R, White S. The Emergence of the Genus Comamonas as Important Opportunistic Pathogens. Pathogens. 2022;11(9): 1032. https://doi.org/10.3390/pathogens11091032.

Parra-Vera HJ, Buele-Chica D, Jiménez-Jiménez AD, Altamirano-Rodas DC, Quinde-Zambrano RM, Morán Vargas CA. Comamonas testosteroni, una breve revisión microbiológica. Ciencia Ecuador. 2021;3(4): 1–9. https://doi.org/10.23936/rce.v3i4.4.

Farfán Cano GG. Comamonas testosteroni. Cohesive Journal of Microbiology & Infectious Disease. 2022;6(3): 1–2. https://doi.org/10.31031/CJMI.2022.06.000636.

Wu Y, Zaiden N, Cao B. The Core- and Pan-Genomic Analyses of the Genus Comamonas: From Environmental Adaptation to Potential Virulence. Frontiers in Microbiology. 2018;9: 3096. https://doi.org/10.3389/fmicb.2018.03096.

Altun E, Kaya B, Taktakoğlu O, Karaer R, Paydas S, Balal M, et al. Comamonas Testosteroni Peritonitis Secondary to Dislocated Intrauterine Device and Laparoscopic Intervention in a Continuous Ambulatory Peritoneal Dialysis Patient. Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 2013;33(5): 576–578. https://doi.org/10.3747/pdi.2013.00007.

BacDive. Comamonas testosteroni DSM 50244 is a mesophilic human pathogen that was isolated from soil, enrichment with testosterone. 2020. https://bacdive.dsmz.de/strain/2923

Cooper GR, Staples ED, Iczkowski KA, Clancy CJ. Comamonas (Pseudomonas) testosteroni endocarditis. Cardiovascular Pathology. 2005;14(3): 145–149. https://doi.org/10.1016/j.carpath.2005.01.008.

Tartar T, Sağmak-Tartar A, Saraç M, Bakal Ü, Akbulut A, Kazez A. Does microbial resistance profile change in community-based intra-abdominal infections? evaluation of the culture results of patients with appendicitis. The Turkish Journal of Pediatrics. 2018;60(5): 520. https://doi.org/10.24953/turkjped.2018.05.008.

Lima-Lucero IM, Castañón González JA, Gorordo-Delsol LA. Neumonía asociada a ventilador por Comamonas testosteroni. Rev Hosp Jua Mex. 2016;83(1 y 2): 56–57. https://www.medigraphic.com/pdfs/juarez/ju-2016/ju161-2i.pdf