Cutaneous histoplasmosis. A case report
DOI:
https://doi.org/10.54034/mic.e1353Keywords:
histoplasma capsulatum infection, aids-related opportunistic infections, histoplasmosis, cutaneous histoplasmosis, HIVAbstract
Histoplasmosis is an endemic infection of Ecuador, its forms of presentation can be varied and florid, especially in immunosuppressed patients, its lethality is high, hence its diagnosis and treatment should be based on both clinical and laboratory results. Cutaneous histoplasmosis is a form of disseminated Histoplasma capsulatum infection rarely described in HIV patients. The following is a description of the diagnosis and treatment of a patient with generalized papular skin lesions, heat stroke, diarrhea, attributed to adverse reaction of gastritis treatment of 10 days of evolution, this was associated with a recent diagnosis of HIV infection following his admission to hospital.
References
Messina FA, Corti M, Negroni R, Arechavala A, Bianchi M, Santiso G. Histoplasmosis en pacientes con SIDA sin manifestaciones cutáneo-mucosas. Revista chilena de infectología. 2018;35(5): 560–565. https://doi.org/10.4067/s0716-10182018000500560.
Romo Erazo M, Gonzalez Roldan A, Gutierrez San Luca V, Plaza Velez L. Histoplasmosis cutánea primaria en pacientes inmunocompetentes Reporte de 2 casos. AVFT. 2019;38(2): 19–21. http://www.revistaavft.com/images/revistas/2019/avft_2_2019/3histoplasmosis_cutanea.pdf
Cortes-Vega F, Iraheta-Nájera E, Ortiz-Barahona J. Intestinal con síntomas de apendicitis aguda en femenina con síndrome de inmunodeficiencia adquirida: Reporte de un caso. Infectio. 2018;22(3): 167–170. http://www.scielo.org.co/pdf/inf/v22n3/0123-9392-inf-22-03-00167.pdf
Badley J. Diagnosis and treatment of histoplasmosis in HIV-infected patients. UpToDate. 2018. https://www.uptodate.com/contents/diagnosis-and-treatment-of-histoplasmosis-inhiv-infected-patients
Pérez-Lazo G, Maquera-Afaray J, Mejia CR, Castillo R. Histoplasmosis diseminada e infección por VIH: serie de casos en un hospital peruano. Revista chilena de infectología. 2017;34(4): 365–369. https://doi.org/10.4067/s0716-10182017000400365.
Morote S, Nacher M, Blaizot R, Ntab B, Blanchet D, Drak Alsibai K, et al. Comparison of Disseminated Histoplasmosis with and without Cutaneo-Mucous Lesions in Persons Living with HIV in French Guiana. Journal of Fungi. 2020;6(3): 133. https://doi.org/10.3390/jof6030133.
Morote S, Nacher M, Blaizot R, Ntab B, Blanchet D, Drak Alsibai K, et al. Temporal trends of cutaneo-mucous histoplasmosis in persons living with HIV in French Guiana: Early diagnosis defuses South American strain dermotropism. Vinetz JM (ed.) PLOS Neglected Tropical Diseases. 2020;14(10): e0008663. https://doi.org/10.1371/journal.pntd.0008663.
Wheat L, Hage C. Histoplasma capsulatum (Histoplasmosis) - Infectious Disease and Antimicrobial Agents. Antimicrobe. 2019; http://www.antimicrobe.org/f06.asp
Couppié P, Aznar C, Carme B, Nacher M. American histoplasmosis in developing countries with a special focus on patients with HIV: diagnosis, treatment, and prognosis. Current Opinion in Infectious Diseases. 2006;19(5): 443–449. https://doi.org/10.1097/01.qco.0000244049.15888.b9.
da Silva Ferreira B, de Araújo Filho JA, Matos Pereira N, de Miranda Godoy L, Borges Lamounier B, Dias Nunes E, et al. Disseminated histoplasmosis in AIDS patients: an urban disease. Experience in a metropolis in the middle east of Brazil. Le Infezioni in Medicina. 2017;25(3): 258–262.
Sirait SP, Bramono K, Hermanto N. Correlation of CD4 counts with clinical and histopathological findings in disseminated histoplasmosis: a 10-year retrospective study. International Journal of Dermatology. 2017;56(9): 926–931. https://doi.org/10.1111/ijd.13679.
Nacher M. Histoplasmosis in Persons Living with HIV. Journal of Fungi. 2019;6(1): 3. https://doi.org/10.3390/jof6010003.
Scully MC, Baddley JW. Epidemiology of Histoplasmosis. Current Fungal Infection Reports. 2018;12(1): 51–58. https://doi.org/10.1007/s12281-018-0309-x.
Koffi D, Bonouman IV, Toure AO, Kouadjo F, N'Gou MRE, Sylla K, et al. Estimates of serious fungal infection burden in Côte d'Ivoire and country health profile. Journal of Medical Mycology. 2021;31(1): 101086. https://doi.org/10.1016/j.mycmed.2020.101086.
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